Carbetocin Acetate
Sekans: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Dış görünüş: Beyaz toz
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Su içeriği(karl Fischer): ≤5.0%
Asetat İçeriği(HPLC tarafından): ≤12.0%
Amino Asit Bileşimi: ± teorik
Saflık (HPLC tarafından): ≥98.0%
Tek Kirlilik(HPLC tarafından): ≤1.0%
Peptit İçeriği(by N%): ≥80%
tahlil(Susuz tarafından, Asetik Asit İçermez ): 97.0~103.0%
Bakteriyel Endotoksinler: ≤5AB/mg
kullanım:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (HAN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
