Karbetocinacetat
Sekvens: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Utseende: hvitt pulver
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Vanninnhold(Karl Fischer): ≤5.0%
Acetatinnhold(ved HPLC): ≤12,0 %
Aminosyresammensetning: ±10 % av teoretisk
Renhet (ved HPLC): ≥98,0 %
Enkel Urenhet(ved HPLC): ≤1,0 %
Peptidinnhold(by N%): ≥80 %
Assay(Av vannfri, Eddiksyrefri ): 97.0~103.0%
Bakterielle endotoksiner: ≤5EU/mg
Bruk:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (VERTSHUS, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) og, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) og, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
