Carbetocin Acetate
توالی: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
ظاهر: پودر سفید
EINECS: 253-312-6
م.ف.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
محتوای آب(کارل فیشر): ≤5.0٪
محتوای استات(توسط HPLC): ≤12.0٪
ترکیب اسید آمینه: ± 10 درصد نظری
خلوص (توسط HPLC): ≥98.0٪
ناخالصی منفرد(توسط HPLC): ≤1.0٪
محتوای پپتید(by N%): ≥80%
سنجش(توسط Anhydrous, بدون اسید استیک ): 97.0~103.0%
اندوتوکسین های باکتریایی: ≤5EU/mg
استفاده:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (INN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) و, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) و, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
