Carbetocin Acetate
Последователност: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Външен вид: Бяла пудра
EINECS: 253-312-6
М.Ф.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Съдържание на вода(Карл Фишер): ≤5,0%
Съдържание на ацетат(чрез HPLC): ≤12,0%
Аминокиселинен състав: ±10% от теоретичната
Чистота (чрез HPLC): ≥98,0%
Единична примес(чрез HPLC): ≤1,0%
Съдържание на пептиди(by N%): ≥80%
Анализ(От Безводен, Без оцетна киселина ): 97.0~103,0%
Бактериални ендотоксини: ≤5EU/mg
Използване:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (КРЪЧМА, БАН) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
