Carbetocin Acetate
Secvenţă: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Aspect: pudră albă
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Continut de apa(Karl Fischer): ≤5.0%
Conținut de acetat(prin HPLC): ≤12,0%
Compoziția aminoacizilor: ±10% din teoretic
Puritate (prin HPLC): ≥98,0%
Impuritate unică(prin HPLC): ≤1.0%
Conținutul de peptide(by N%): ≥80%
Test(Prin Anhidru, Fara acid acetic ): 97.0~103,0%
Endotoxine bacteriene: ≤5EU/mg
Utilizare:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (HAN, INTERZICE) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) și, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) și, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
