Carbetocin Acetate
Zaporedje: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Videz: Bel prah
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Vsebnost vode(Karl Fischer): ≤5.0%
Vsebnost acetata(s HPLC): ≤12,0 %
Aminokislinska sestava: ±10 % teoretičnega
Čistost (s HPLC): ≥98,0 %
Ena nečistoča(s HPLC): ≤1,0 %
Vsebnost peptidov(by N%): ≥80 %
Esej(Avtor Anhydrous, Brez ocetne kisline ): 97.0~103.0%
Bakterijski endotoksini: ≤5EU/mg
Uporaba:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (GOSTILNA, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
