Carbetocin Acetate
Последовательность: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
КАС: 37025-55-1
вид: белый порошок
ЭИНЕКС: 253-312-6
М.Ф.: C45H69N11O12S
М.В.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Содержание воды(Карл Фишер): ≤5,0%
Содержание ацетата(методом ВЭЖХ): ≤12,0%
Аминокислотный состав: ±10% от теоретического
Чистота (методом ВЭЖХ): ≥98,0%
Одиночная примесь(методом ВЭЖХ): ≤1,0%
Содержание пептидов(by N%): ≥80%
анализ(Безводный, Без уксусной кислоты ): 97.0~103,0%
Бактериальные эндотоксины: ≤5EU/мг
Применение:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (ГОСТИНИЦА, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) и, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
