Carbetocin Acetate
Secuencia: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Apariencia: polvo blanco
EINECS: 253-312-6
M. F.: C45H69N11O12S
MW: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Contenido de agua(karl fischer): ≤5.0%
Contenido de acetato(por HPLC): ≤12,0%
Composición de aminoácidos: ±10% del teórico
Pureza (por HPLC): ≥98,0%
impureza única(por HPLC): ≤1,0%
Contenido de péptidos(by N%): ≥80%
Ensayo(por anhidro, Libre de ácido acético ): 97.0~103,0%
Endotoxinas bacterianas: ≤5EU/mg
Uso:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (POSADA, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
