Carbetocin Acetate
Sekvencia: Butyryl-Tyr(ja)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfidová väzba medzi butyryl-4-ylom a Cys)
CAS: 37025-55-1
Vzhľad: Biely prášok
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Špecifická optická rotácia D(c = 1,1 % HAc): -38.0~-42.0°
Obsah vody(Karl Fischer): ≤ 5,0 %
Obsah acetátu(pomocou HPLC): ≤ 12,0 %
Aminokyselinové zloženie: ±10 % teoretickej hodnoty
Čistota (pomocou HPLC): ≥98,0 %
Jediná nečistota(pomocou HPLC): ≤ 1,0 %
Obsah peptidov(o N %): ≥ 80 %
Skúška(Bezvodý, Bez kyseliny octovej ): 97.0~103,0 %
Bakteriálne endotoxíny: ≤ 5 EU/mg
Použitie:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (INN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) a, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) a, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
