Carbetocin Acetate
Sequentia: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Aspectus: Pulvis albus
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Aqua Content(Carolus Fischer): ≤5.0%
Acetate Content(per HPLC *): ≤12.0%
Amino Acidum Compositio: ± X% speculationis
Puritas (per HPLC *): ≥98.0%
una immunditia(per HPLC *): ≤1.0%
Peptide Content(by N%): ≥80%
Assay(per Anhydrous, Acidum aceticum-liberum ): 97.0~103.0%
Bacterial Endotoxins: ≤5EU/mg
Consuetudinem:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (TABERNA, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) et, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
