Carbetocin Acetate
Sequenza: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Aspetto esteriore: polvere bianca
EINECS: 253-312-6
MF: C45H69N11O12S
MW: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Contenuto di acqua(Karl Fischer): ≤5.0%
Contenuto in acetato(da HPLC): ≤12,0%
Composizione di amminoacidi: ±10% del teorico
Purezza (da HPLC): ≥98,0%
Singola impurità(da HPLC): ≤1,0%
Contenuto peptidico(by N%): ≥80%
Saggio(Di Anidro, Senza acido acetico ): 97.0~103,0%
Endotossine batteriche: ≤5EU/mg
Utilizzo:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (LOCANDA, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) E, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) E, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
