Karbetocinacetat
Sekvens: Butyryltjur(Mig)-Ile-gln-asn-cys-pro-leu-gly-nh2 (Sulfidbindning mellan butyryl-4-yl och cys)
CAS: 37025-55-1
Utseende: vitt pulver
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specifik optisk rotation d(c = 1,1%HAC): -38.0~-42.0°
Vatten innehåll(Karl Fischer): ≤5,0 %
Acetatinnehåll(genom HPLC): ≤12,0 %
Aminosyrasammansättning: ±10 % av det teoretiska
Renhet (genom HPLC): ≥98,0 %
Enkel förorening(genom HPLC): ≤1,0 %
Peptidinnehåll(av n%): ≥80 %
Analysera(Av Vattenfri, Ättiksyrafri ): 97.0~103,0 %
Bakteriella endotoxiner: ≤5EU/mg
Användande:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (VÄRDSHUS, FÖRBJUDA) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) och, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) och, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
