Carbetocin Acetate
Seqüência: Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Sulfide bond between Butyryl-4-yl and Cys)
CAS: 37025-55-1
Aparência: pó branco
EINECS: 253-312-6
M.F.: C45H69N11O12S
M.W.: 988.17
Specific Optical Rotation D(c=1,1%HAc): -38.0~-42.0°
Teor de Água(Karl Fischer): ≤5.0%
Conteúdo de acetato(por HPLC): ≤12,0%
Composição de Aminoácidos: ±10% do teórico
Pureza (por HPLC): ≥98,0%
Impureza Única(por HPLC): ≤1,0%
Conteúdo Peptídeo(by N%): ≥80%
Ensaio(Por Anidro, Sem ácido acético ): 97.0~103,0%
Endotoxinas bacterianas: ≤5EU/mg
Uso:An obstetric drug used to control postpartum hemorrhaging.
Carbetocin (POUSADA, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
Carbetocin is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight amino acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.
