наименование товара :Кальцитониновый лосось
Торговое название:Сейлтона
КАС №:47931-85-1
Молекулярная формула: C145H240N44O48S2
Молекулярный вес:3431.85г/моль
Чистота : 98% ВЭЖХ
вид: Лиофилизированный порошок
Типичное использование:Лечение остеопороза
кальцитонин (salmon) is an hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Increase of bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture
-Treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture
| Item |
Стандартный |
Результаты теста |
| Удостоверение личности |
A.H-NMR:Comply with the structure |
Соответствует |
|
B.LC-MS:Comply with the structure |
Соответствует |
|
C.The IR spectrum of sample should be identical with that of reference standard; |
Соответствует |
|
D.HPLC-ESI-MS
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Соответствует |
| Crystallinity |
meets the requirements. |
Соответствует |
| Убыток от высыхания |
≤2,0% |
0.19% |
| Тяжелые металлы |
≤10 ppm |
<10частей на миллион |
| Вода |
≤1,0% |
0.1% |
| Сульфатная зола |
≤0,5%, determined on 1.0 грамм. |
0.009% |
| Связанные вещества |
Unspecified impurities: for each impurity |
<0.10% |
|
Общая примесь |
0.18% |
| Чистота |
≥99,0% |
99.7% |
| анализ |
99.0%~101,0% (anhydrous substance). |
99.8% |
| Microbiological Analysis |
|
|
| Total plate count |
≤1000 КОЕ/г |
Соответствует |
| Yeast and Moulds |
≤100cfu/g |
Соответствует |
| Е. Coli. |
Absent |
Отрицательный |
| сальмонелла |
Absent |
Отрицательный |
| S.aureus |
Absent |
Отрицательный |
| Хранилище |
Preserve in well-closed, light-resistant and airtight containers. |
Соответствует |
