setroreliks asetat
İngilizce Eşanlamlılar: N-Asetil-3-(2-naftalenil)-D-alanil-4-kloro-D-fenilalanil-3-(3-piridinil)-D-alanil-L-seril-L-tirosil-N5-(aminokarbonil)-D-ornitil-L-leusil-L-arginil-L-prolil-D-alaninamid diasetat;setroreliks asetat;setrorenlin asetat
CAS: 130143-01-0
tahlil: 98%
Moleküler formül: C70H92N17O14
Moleküler ağırlık:1551.16
kullanım: GnRH reseptör antagonistini teşvik etmektir
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Items |
Özellikler |
Sonuçlar |
| Dış görünüş |
Beyaz toz |
Beyaz toz |
| Identity by HPLC |
The retention is same with the reference substance |
uygun |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Amino Asit Bileşimi |
±20% of theoretical |
uygun |
| Saflık (HPLC tarafından) |
≥98.0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2.0%
Largest Single Impurity(%)≤1.0% |
0.89%
0.25% |
| Asetat İçeriği (HPLC tarafından) |
≤15.0% |
9.7% |
| Su içeriği (by Karl Fischer) |
≤10.0 |
2.2% |
| Bakteriyel Endotoksinler |
≤5AB/mg |
uygun |
| Peptit İçeriği(N%) |
≥85.0% |
86.5% |
