セトロレリックス酢酸塩
英語の同義語: N-アセチル-3-(2-ナフタレニル)-D-アラニル-4-クロロ-D-フェニルアラニル-3-(3-ピリジニル)-D-アラニル-L-セリル-L-チロシル-N5-(アミノカルボニル)-D-オルニチル-L-ロイシル-L-アルギニル-L-プロリル-D-アラニンアミドジアセテート;セトロレリックス酢酸塩;酢酸セトロレンリン
CAS: 130143-01-0
アッセイ: 98%
分子式: C70H92N17O14
分子量:1551.16
使用法: GnRH受容体拮抗薬を促進することです
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| アイテム |
仕様 |
結果 |
| 外観 |
白い粉 |
白い粉 |
| Identity by HPLC |
The retention is same with the reference substance |
適合 |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| アミノ酸組成 |
±20% of theoretical |
適合 |
| 純度 (HPLCによる) |
≧98.0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2.0%
Largest Single Impurity(%)≤1.0% |
0.89%
0.25% |
| アセテート含有量 (HPLCによる) |
≤15.0% |
9.7% |
| 含水量 (by Karl Fischer) |
≤10.0% |
2.2% |
| 細菌エンドトキシン |
≤5EU/mg |
適合 |
| ペプチド含有量(N%) |
≥85.0% |
86.5% |
