Cetrorelix-acetaat
Engelse synoniemen: N-Acetyl-3-(2-naftalenyl)-D-alanyl-4-chloor-D-fenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alanineamidediacetaat;Cetrorelix-acetaat;Cetrorenline-acetaat
CAS: 130143-01-0
Assay: 98%
Moleculaire formule: C70H92N17O14
Molecuulgewicht:1551.16
Gebruik: Is het bevorderen van de GnRH-receptorantagonist
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Items |
Specificaties: |
Results |
| Uiterlijk |
wit poeder |
wit poeder |
| Identity by HPLC |
The retention is same with the reference substance |
Conforms |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Aminozuursamenstelling |
±20% of theoretical |
Conforms |
| Zuiverheid (door HPLC) |
≥98,0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2,0%
Largest Single Impurity(%)≤1.0% |
0.89%
0.25% |
| Acetaat inhoud (door HPLC) |
≤15.0% |
9.7% |
| Water inhoud (by Karl Fischer) |
≤10,0% |
2.2% |
| Bacteriële endotoxinen |
≤5EU/mg |
Conforms |
| Peptide-inhoud(N%) |
≥85.0% |
86.5% |
