Cetrorelix-asetaat
Engelse sinonieme: N-asetiel-3-(2-naftaleniel)-D-alaniel-4-chloor-D-fenielalaniel-3-(3-piridiniel)-D-alaniel-L-seriel-L-tirosiel-N5-(aminokarboniel)-D-ornitiel-L-leusiel-L-arginiel-L-prolyl-D-alaninamied diasetaat;Cetrorelix-asetaat;Cetrorenlin asetaat
CAS: 130143-01-0
Toets: 98%
Molekulêre Formule: C70H92N17O14
Molekulêre gewig:1551.16
Gebruik: Is om die GnRH reseptor antagonis te bevorder
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Items |
Spesifikasies |
Resultate |
| Voorkoms |
Wit poeier |
Wit poeier |
| Identity by HPLC |
The retention is same with the reference substance |
Conforms |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Aminosuur samestelling |
±20% of theoretical |
Conforms |
| Reinheid (deur HPLC) |
≥98,0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Asetaat inhoud (deur HPLC) |
≤15,0% |
9.7% |
| Waterinhoud (by Karl Fischer) |
≤10,0% |
2.2% |
| Bakteriese endotoksiene |
≤5EU/mg |
Conforms |
| Peptied inhoud(N%) |
≥85.0% |
86.5% |
