Cetrorelix acetat
Sinonime în engleză: N-acetil-3-(2-naftalenil)-D-alanil-4-clor-D-fenilalanil-3-(3-piridinil)-D-alanil-L-seril-L-tirosil-N5-(aminocarbonil)-diacetat de D-ornitil-L-leucil-L-arginil-L-prolil-D-alaninamidă;Cetrorelix acetat;Acetat de Cetrorenlin
CAS: 130143-01-0
Test: 98%
Formulă moleculară: C70H92N17O14
Greutate moleculară:1551.16
Utilizare: Este de a promova antagonistul receptorului GnRH
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Articole |
Specificații |
Rezultate |
| Aspect |
pudră albă |
pudră albă |
| Identity by HPLC |
The retention is same with the reference substance |
Se conformează |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Compoziția aminoacizilor |
±20% of theoretical |
Se conformează |
| Puritate (prin HPLC) |
≥98,0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Conținut de acetat (prin HPLC) |
≤15,0% |
9.7% |
| Continut de apa (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotoxine bacteriene |
≤5EU/mg |
Se conformează |
| Conținutul de peptide(N%) |
≥85.0% |
86.5% |
