Cetrorelix acetato
Sinonimi inglesi: N-acetil-3-(2-naftalenile)-D-alanil-4-cloro-D-fenilalalanil-3-(3-piridinile)-D-alanil-L-seril-L-tirosil-N5-(amminocarbonile)-Diacetato di D-ornitil-L-leucil-L-arginil-L-prolil-D-alaninamide;Cetrorelix acetato;Acetato di cetrorenlina
CAS: 130143-01-0
Saggio: 98%
Formula molecolare: C70H92N17O14
Peso molecolare:1551.16
Utilizzo: È quello di promuovere l'antagonista del recettore del GnRH
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Elementi |
specificazioni |
Risultati |
| Aspetto esteriore |
polvere bianca |
polvere bianca |
| Identity by HPLC |
The retention is same with the reference substance |
Conforme |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Composizione di amminoacidi |
±20% of theoretical |
Conforme |
| Purezza (da HPLC) |
≥98,0% |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2,0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Contenuto in acetato (da HPLC) |
≤15,0% |
9.7% |
| Contenuto di acqua (by Karl Fischer) |
≤10,0% |
2.2% |
| Endotossine batteriche |
≤5EU/mg |
Conforme |
| Contenuto peptidico(N%) |
≥85.0% |
86.5% |
