Acétate de cétrorélix
Synonymes anglais: N-acétyl-3-(2-naphtalényle)-D-alanyl-4-chloro-D-phénylalanyl-3-(3-pyridinyle)-D-alanyl-L-séryl-L-tyrosyl-N5-(aminocarbonyle)-Diacétate de D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide;Acétate de cétrorélix;Acétate de cétrorenline
CAS: 130143-01-0
Essai: 98%
Formule moléculaire: C70H92N17O14
Masse moléculaire:1551.16
Usage: Est de promouvoir l'antagoniste des récepteurs de la GnRH
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Articles |
Caractéristiques |
Résultats |
| Apparence |
poudre blanche |
poudre blanche |
| Identity by HPLC |
The retention is same with the reference substance |
Conforme |
| Specific Optical Rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Composition en acides aminés |
±20% of theoretical |
Conforme |
| Pureté (par CLHP) |
≥98,0 % |
99.11% |
| Related Substance(By HPLC) |
Total Impurities(%)≤2.0%
Largest Single Impurity(%)≤1,0% |
0.89%
0.25% |
| Teneur en acétate (par CLHP) |
≤15,0 % |
9.7% |
| Teneur en eau (by Karl Fischer) |
≤10,0 % |
2.2% |
| Endotoxines bactériennes |
≤5EU/mg |
Conforme |
| Teneur en peptides(N %) |
≥85.0% |
86.5% |
