Cetrorelixacetat
Engelska synonymer: N-acetyl-3-(2-naftalenyl)-D-alanyl-4-klor-D-fenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminokarbonyl)-D-ornityl-L-leucyl-L-arginyl-L-prolyl-D-alaninamiddiacetat;Cetrorelixacetat;Cetrorenlinacetat
CAS: 130143-01-0
Analysera: 98%
Molekylär formel: C70H92N17O14
Molekylvikt:1551.16
Användande: Är att främja GnRH-receptorantagonisten
Cetrorelix acetate is the acetic acid salt of cetrorelix. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. It has a role as a GnRH antagonist and an antineoplastic agent. It is an oligopeptide and an acetate salt. It contains a cetrorelix.
The use of cetrorelix is contraindicated in severe renal impairment. It is not intended for women aged 65 years or older. Use in women with severe allergic conditions is not recommended. Use with caution in women with active allergies or history of allergies.
| Föremål |
Specifikationer |
Resultat |
| Utseende |
vitt pulver |
vitt pulver |
| Identity by HPLC |
The retention is same with the reference substance |
Överensstämmer |
| Specifik optisk rotation |
-20 to -30°(c=1,50%HAc) |
-26.5° |
| Aminosyrasammansättning |
±20% of theoretical |
Överensstämmer |
| Renhet (genom HPLC) |
≥98,0 % |
99.11% |
| Relaterat ämne(Genom HPLC) |
Totala föroreningar(%)≤2,0 %
Largest Single Impurity(%)≤1,0 % |
0.89%
0.25% |
| Acetatinnehåll (genom HPLC) |
≤15,0 % |
9.7% |
| Vatten innehåll (by Karl Fischer) |
≤10,0 % |
2.2% |
| Bakteriella endotoxiner |
≤5EU/mg |
Överensstämmer |
| Peptidinnehåll(N%) |
≥85.0% |
86.5% |
