od Elcatona
vzdevek:kalcinil,karbikalcin,karbokalcitonin,od Elcatona, Elcitonova, Turbokalcin
ŠT. CAS. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Videz : Bel prah
Čistost : 98%
Ocena : Farmacevtski razred
Vsebnost peptidov(avtor %N): ≥80 %
Vsebnost vode(Karl Fischer): ≤8,0 %
Vsebnost acetata(s HPLC): ≤12,0 %
Aminokislinska sestava: ±10 % teoretičnega
Čistost(s HPLC): 98.0%min.
Ena nečistoča(s HPLC): 0.5%maks.
Esej(Avtor Anhydrous, Brez ocetne kisline): 95.0~105,0 %
GOSPA: Dosledno
Shranjevanje: Hladno suho mesto(-20℃, stran od svetlobe)
Uporaba : Elcatonin se uporablja za hiperkalcemijo, osteoporoza.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino kisline, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Vsebnost vode(Karl Fischer) :≤10,0 %
Vsebnost acetata(s HPLC) :≤15,0 %
Aminokislinska sestava :±10 % teoretičnega
Čistost (s HPLC) :≥98,0 %
Ena nečistoča(s HPLC) :≤1,0 %
Vsebnost peptidov(avtor %N) :≥80 %
Esej(Avtor Anhydrous, Brez ocetne kisline ) :95.0~105,0 %
Bakterijski endotoksini :≤5EU/mg
