van Elcaton
Alias:Calcinil,Carbicalcin,Karbokalsitonien,van Elcaton, Die van Elciton, Turbocalcin
CAS NO. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Voorkoms : Wit poeier
Reinheid : 98%
Graad : Farmaseutiese Graad
Peptied inhoud(deur %N): ≥80%
Waterinhoud(Karl Fischer): ≤8,0%
Asetaat inhoud(deur HPLC): ≤12,0%
Aminosuur samestelling: ±10% van teoreties
Reinheid(deur HPLC): 98.0%min.
Enkele Onreinheid(deur HPLC): 0.5%maks.
Toets(Deur Anhydrous, Asynsuurvry): 95.0~105,0%
MS: Konsekwent
Berging: Koel droë plek(-20℃, weg van die lig)
Gebruik : Elkatonien word gebruik vir hiperkalsemie, osteoporose.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Daarby, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 aminosure, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Daarby, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Waterinhoud(Karl Fischer) :≤10,0%
Asetaat inhoud(deur HPLC) :≤15,0%
Aminosuur samestelling :±10% van teoreties
Reinheid (deur HPLC) :≥98,0%
Enkele Onreinheid(deur HPLC) :≤1,0%
Peptied inhoud(deur %N) :≥80%
Toets(Deur Anhydrous, Asynsuurvry ) :95.0~105,0%
Bakteriese endotoksiene :≤5EU/mg
