de Elcaton
Alias:Calcinil,Carbicalcina,Carbocalcitonina,de Elcaton, Elciton's, Turbocalcina
Nº CAS. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Aparência : pó branco
Pureza : 98%
Avaliar : Grau Farmacêutico
Conteúdo Peptídeo(por %N): ≥80%
Teor de Água(Karl Fischer): ≤8,0%
Conteúdo de acetato(por HPLC): ≤12,0%
Composição de Aminoácidos: ±10% do teórico
Pureza(por HPLC): 98.0%min.
Impureza Única(por HPLC): 0.5%máximo.
Ensaio(Por Anidro, Sem ácido acético): 95.0~105,0%
EM: Consistente
Armazenar: Lugar seco fresco(-20℃, longe da luz)
Uso : Elcatonina é usado para hipercalcemia, osteoporose.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 aminoácidos, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Teor de Água(Karl Fischer) :≤10,0%
Conteúdo de acetato(por HPLC) :≤15,0%
Composição de Aminoácidos :±10% do teórico
Pureza (por HPLC) :≥98,0%
Impureza Única(por HPLC) :≤1,0%
Conteúdo Peptídeo(por %N) :≥80%
Ensaio(Por Anidro, Sem ácido acético ) :95.0~105,0%
Endotoxinas bacterianas :≤5EU/mg
