av Elcaton
Alias:Calcinil,Carbicalcin,Karbokalsitonin,av Elcaton, Elciton sin, Turbocalcin
CAS NR. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Utseende : hvitt pulver
Renhet : 98%
Karakter : Farmasøytisk karakter
Peptidinnhold(av %N): ≥80 %
Vanninnhold(Karl Fischer): ≤8,0 %
Acetatinnhold(ved HPLC): ≤12,0 %
Aminosyresammensetning: ±10 % av teoretisk
Renhet(ved HPLC): 98.0%min.
Enkel Urenhet(ved HPLC): 0.5%maks.
Assay(Av vannfri, Eddiksyrefri): 95.0~105,0 %
MS: Konsistent
Oppbevaring: Kjølig tørt sted(-20℃, vekk fra lyset)
Bruk : Elcatonin brukes mot hyperkalsemi, osteoporose.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. I tillegg, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 aminosyrer, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. I tillegg, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Vanninnhold(Karl Fischer) :≤10,0 %
Acetatinnhold(ved HPLC) :≤15,0 %
Aminosyresammensetning :±10 % av teoretisk
Renhet (ved HPLC) :≥98,0 %
Enkel Urenhet(ved HPLC) :≤1,0 %
Peptidinnhold(av %N) :≥80 %
Assay(Av vannfri, Eddiksyrefri ) :95.0~105,0 %
Bakterielle endotoksiner :≤5EU/mg
