di Elcaton
Alias:calcinil,Carbicalcina,Carbocalcitonina,di Elcaton, di Elcito, Turbocalcina
N. CAS. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Aspetto esteriore : polvere bianca
Purezza : 98%
Grado : Grado farmaceutico
Contenuto peptidico(di %N): ≥80%
Contenuto di acqua(Karl Fischer): ≤8,0%
Contenuto in acetato(da HPLC): ≤12,0%
Composizione di amminoacidi: ±10% del teorico
Purezza(da HPLC): 98.0%min.
Singola impurità(da HPLC): 0.5%max.
Saggio(Di Anidro, Senza acido acetico): 95.0~105,0%
SM: Coerente
Magazzinaggio: Luogo fresco e asciutto(-20℃, lontano dalla luce)
Utilizzo : Elcatonin è usato per l'ipercalcemia, osteoporosi.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Inoltre, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 aminoacidi, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. Inoltre, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Contenuto di acqua(Karl Fischer) :≤10,0%
Contenuto in acetato(da HPLC) :≤15,0%
Composizione di amminoacidi :±10% del teorico
Purezza (da HPLC) :≥98,0%
Singola impurità(da HPLC) :≤1,0%
Contenuto peptidico(di %N) :≥80%
Saggio(Di Anidro, Senza acido acetico ) :95.0~105,0%
Endotossine batteriche :≤5EU/mg
