Elcatonin
Alias:Calcinil,Carbicalcin,Carbocalcitonin,Elcatonin, Elcitonin, Turbocalcin
CAS NO. : 60731-46-6
EINECS : 262-393-7
MF : C148H244N42O47
MW : 3363.82
Appearance : White powder
Purity : 98%
Grade : Pharmaceutical Grade
Peptide Content(by %N): ≥80%
Water Content(Karl Fischer): ≤8.0%
Acetate Content(by HPLC): ≤12.0%
Amino Acid Composition: ±10% of theoretical
Purity(by HPLC): 98.0%min.
Single Impurity(by HPLC): 0.5%max.
Assay(By Anhydrous, Acetic Acid-free): 95.0~105.0%
MS: Consistent
Storage: Cool dry place(-20℃, away from the light)
Usage : Elcatonin is used for Hypercalcemia, osteoporosis.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Elcatonin is a Calcitonin derivative which is transformed from eel's calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.
Water Content(Karl Fischer) :≤10.0%
Acetate Content(by HPLC) :≤15.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
