Secretin
Sequentia:H-Ser-Asp-Gly Thr-Phe-Ser-Glu-Leu-Ser-Arg-Leu-Asp Gly-Leu-Val-NH2
alias : Secretin, Sus secretin, Porcine secretin, Secrepan, Secretin-Ferring, Secretolin,Humanum Secretin
Cas No.: 17034-35-4
EINECS : 241-105-3
Formulae hypotheticae: C130H220N44O41
M. Pondus: 3055.47
Puritas (HPLC): 98.0%min.
Aspectus: Pulvis albus
una immunditia (HPLC): 1.0%max
Amino Acidum Compositio: ± X% speculationis
Peptide Content (N%): >80.0%
Aqua Content(Carolus Fischer): <6.0%
Acetate Content (HPIC): <15.0%
MS(ESI): Congruunt
Massa Libra: 95.0~105.0%
Gradus : Pharmaceutical Grade
Repono: Clausa, infra 2 ~ 8℃ conservatio
Consuetudinem : Secretin acetas hormona est quae duodeni ambitum regere tenetur, secretiones pancreaticae et ventriculi moderans aquam homeostasin per corpus animalis.. Specie, duodenum pH moderari iuvat, inhibendo secretionem acidi gastrici ex cellulis parietalibus stomachi et stimulationem productionis bicarbonatae in centroacinar cellulis a pancreate crescentibus..
Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands.In humans, the secretin peptide is encoded by the SCT gene.
Secretin helps regulate the pH of the duodenum by inhibiting the secretion of gastric acid from the parietal cells of the stomach and stimulating the production of bicarbonate from the ductal cells of the pancreas.It also stimulates the secretion of bicarbonate and water by cholangiocytes in the bile duct, protecting it from bile acids by controlling the pH and promoting the flow in the duct.Meanwhile, in concert with secretin's actions, the other main hormone simultaneously issued by the duodenum, cholecystokinin (CCK), is stimulating the gallbladder to contract, delivering its stored bile.
