Назва продукту: Ларазотид
Номер CAS:258818-34-7
Послідовність:Гліцилгліцил-L-валіл-L-лейцил-L-валіл-L-глутамініл-L-пролілгліцин
Молекулярна формула: C32H55N9O10
Молекулярна маса: 725.83 г/моль
Специфікація: 1mg/Vials
Чистота : 98% ВЕРХ
Зовнішній вигляд: Білий ліофілізований порошок
Типове використання: Celiac Therapy
Стандартна упаковка: 10vials/kits
Ларазотид (ГОТЕЛЬ; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine.
