Nom du produit: Larazotide
n ° CAS:258818-34-7
Séquence:Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine
Formule moléculaire: C32H55N9O10
Masse moléculaire: 725.83 g/mole
spécification: 1mg/flacons
Pureté : 98% CLHP
Apparence: Poudre lyophilisée blanche
Utilisation typique: Celiac Therapy
Emballage standard: 10flacons/kits
Larazotide (AUBERGE; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine.
