Meno Produktu: Larazotid
CAS č:258818-34-7
Sekvencia:Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycín
Molekulárny vzorec: C32H55N9O10
Molekulová hmotnosť: 725.83 g/mol
Špecifikácia: 1mg/Vials
Čistota : 98% HPLC
Vzhľad: Biely lyofilizovaný prášok
Typické použitie: Celiac Therapy
Štandardné balenie: 10vials/kits
Larazotid (INN; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine.
