Nazwa produktu: Larazotyd
Nr CAS:258818-34-7
Sekwencja:Glicyloglicylo-L-walilo-L-leucylo-L-walilo-L-glutaminyl-L-proliloglicyna
Formuła molekularna: C32H55N9O10
Waga molekularna: 725.83 g/mol
Specyfikacja: 1mg/fiolki
Czystość : 98% HPLC
Wygląd zewnętrzny: Biały liofilizowany proszek
Typowe zastosowanie: Celiac Therapy
Standardowe pakowanie: 10fiolki/zestawy
Larazotyd (ZAJAZD; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-Ł-valyl-Ł-leucyl-Ł-valyl-Ł-glutaminyl-Ł-prolyl-glycine.
