商品名: ララゾチド
CAS番号:258818-34-7
順序:グリシルグリシル-L-バリル-L-ロイシル-L-バリル-L-グルタミニル-L-プロリルグリシン
分子式: C32H55N9O10
分子量: 725.83 グラム/モル
仕様: 1mg/Vials
純度 : 98% HPLC
外観: 白色凍結乾燥粉末
典型的な使用: Celiac Therapy
標準梱包: 10vials/kits
ララゾチド (宿; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
Larazotide is an octapeptide whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae. It has the amino acid sequence GGVLVQPG, IUPAC condensed descriptor of H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH, and the systematic name glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine.
