China Anabolic Steroids Powder Manufacturer
EnglishAfrikaansБългарскиNederlandsFrançaisDeutschItaliano日本語LatīnaNorskپارسیPolskiPortuguêsRomânăРусскийSlovenčinaSlovenščinaEspañolSvenskaTürkçeУкраїнськаудмурт кыл

Pharmaceutical Peptides

» Peptides » Pharmaceutical Peptides

  • Specifications
  • Product Description
  • Product Usage

Product Name:Ziconotide Acetate,Prialt
CAS Registry Number: 107452-89-1
Molecular Formula: C102H172N36O32S7
Molecular Weight: 2639.01
Sequence: Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2(Disfulde Bridge: 1-16, 8-20, 15-25)
Appearance: White Powder
Grade: Pharmaceutical Grade
Water Content(Karl Fischer): 5.0%
Acetate Content(by HPLC): 12.0%
Amino Acid Composition: 10% of theoretical
Purity(by HPLC): 98.0%
Single Impurity(by HPLC): 1.0%
Peptide Content(by %N ): 80%
Assay(By Anhydrous, Acetic Acid-free ): 95.0~105.0%
Storage: Cool(2~8 ) & dry place protected from light, keep package close when not in use.

Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail Conus magus comprising 25 amino acids with three disulphide bonds. Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be synthesized without loss of proper bond formation or structural elements.Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.

Ziconotide is an N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.

Ziconotide inhibits N-type calcium channels involved in nociceptive signalling, primarily in the dorsal horn of the spinal cord.Although binding is reversible, careful dosing is required to ensure therapeutic effects while minimizing adverse effects, and ziconotide has been described as possessing a narrow therapeutic window.Patients taking ziconontide may experience cognitive and neuropsychiatric symptoms, reduced levels of consciousness, and elevated serum creatine kinase levels. In addition, ziconotide may increase the risk of infection, including serious cases of meningitis. Patients who withdraw from opiates for ziconotide initiation are advised to taper off the dose.

Enquiry Form ( we will get back you as soon as possible )

Name:
*
Email:
*
Message:

Verification:
5 + 9 = ?

Maybe you like also

  • Our Advantage

    Good Price

    High Quality

    Fast Delivery

    Safe Shipment

    Excellent After-sale Service

  • Local Warehouse

    EU Warehouse

    UK Warehouse

    USA Warehouse

    Canada Warehouse

    Australia Warehouse

  • Payment Method

    Paypal

    Bitcoin

    Bank Wire

    Money Gram

    Western Union

  • Contact Us

    Email: jacob@steroid-peptide.com

    WhatsApp: +8615636286252

    Phone: 0086-15636286252

    Website: www.steroid-peptide.com

    Welcome your inquiry