имя: Dibucaine Hydrochloride
КАС №: 61-12-1
Формула: C20H30ClN3O2
Молекулярный вес: 379.98
Синонимы: 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (9КИ);Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (8КИ);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;
ЭИНЕКС: 200-498-1
Плотность: 1.071г/см3
Температура плавления: 99-101 °С(горит)
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.
1. Dibucaine hydrochloride is a local anesthetic of the amide-type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted.
2. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. In combination sodium, dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration, or other methods in compliance with state and local laws.
| Item |
Стандартный |
Результаты теста |
| Убыток от высыхания |
≤2,0% |
0.19% |
| Тяжелые металлы |
≤10 ppm |
<10частей на миллион |
| Вода |
≤1,0% |
0.10% |
| Сульфатная зола |
≤0,5%, determined on 1.0 грамм. |
0.01% |
| Связанные вещества |
Unspecified impurities: for each impurity |
≤0,10% |
<0.10% |
| Общая примесь |
≤0,5% |
0.18% |
| Чистота |
≥99,0% |
99.70% |
| анализ |
99.0%~101,0% (anhydrous substance). |
99.80% |
| Microbiological Analysis |
| Total plate count |
≤1000 КОЕ/г |
Соответствует |
| сальмонелла |
Absent |
Отрицательный |
| Хранилище |
Preserve in well-closed, light-resistant and airtight containers. |
Соответствует |
