Име: Dibucaine Hydrochloride
CAS номер: 61-12-1
Формула: C20H30ClN3O2
Молекулно тегло: 379.98
Синоними: 4-Quinolinecarboxamide,2-butoxy-N-[2-(диетиламино)етил]-, monohydrochloride (9CI);Cinchoninamide,2-butoxy-N-[2-(диетиламино)етил]-, monohydrochloride (8CI);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;
EINECS: 200-498-1
Плътност: 1.071g/cm3
Точка на топене: 99-101 °C(осветен)
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.
1. Dibucaine hydrochloride is a local anesthetic of the amide-type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted.
2. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. In combination sodium, dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration, or other methods in compliance with state and local laws.
| Вещ |
Стандартен |
Резултати от тестовете |
| Загуба при сушене |
≤2,0% |
0.19% |
| Тежки метали |
≤10 ppm |
<10ppm |
| вода |
≤1,0% |
0.10% |
| Sulphated ash |
≤0,5%, determined on 1.0 ж. |
0.01% |
| Сродни вещества |
Unspecified impurities: for each impurity |
≤0,10% |
<0.10% |
| Пълна примес |
≤0,5% |
0.18% |
| Чистота |
≥99,0% |
99.70% |
| Анализ |
99.0%~101,0% (anhydrous substance). |
99.80% |
| Микробиологичен анализ |
| Total plate count |
≤1000cfu/g |
Съответства |
| Салмонела |
Absent |
Отрицателна |
| Съхранение |
Preserve in well-closed, light-resistant and airtight containers. |
Съответства |
