[ Последовательность ] Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(интеллектуальная собственность)-Про-Д-Ала-NH2
[ Синонимы ] ИЦП 149 ацетат; пленаксис;Абареликс
[ № КАС. ] 183552-38-7
[ Молекулярная формула ] C74H99ClN14O16
[ Молекулярный вес ] 1476.138
[ Плотность ] 1.287 г/см3
[ Точка кипения ] 1688.37 °С при 760 мм рт.ст.
[ Точка возгорания ] 974.891 °С
[ вид ] Белый порошок
[ Заявление ] Активные фармацевтические ингредиенты
[ Чистота ] 98%
[ Основная функция ]
Только научные исследования, нет прямого использования для человеческого тела
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (левый) and follicle stimulating hormone (ФСГ). In males, the inhibition of LH secretion prevents the release of testosterone. В результате, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth.
Abarelix Acetate is an injectable gonadotropin-releasing hormone antagonist (GnRH antagonist). Abarelix Acetate is primarily used in oncology to reduce the amount made in patients with advanced symptomatic prostate cancer for which no other treatment options are available.
