[ Secuencia ] Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(derechos de propiedad intelectual)-Pro-D-Ala-NH2
[ Sinónimos ] IPP 149 acetato; plenaxis;Abarélix
[ NO CAS. ] 183552-38-7
[ Fórmula molecular ] C74H99ClN14O16
[ Peso molecular ] 1476.138
[ Densidad ] 1.287 g/cm3
[ Punto de ebullición ] 1688.37 °C a 760 mmHg
[ Punto de inflamabilidad ] 974.891 ºC
[ Apariencia ] Polvo blanco
[ Solicitud ] Ingredientes farmacéuticos activos
[ Pureza ] 98%
[ Función principal ]
Solo investigacion cientifica, sin uso directo para el cuerpo humano
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. Como resultado, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth.
Abarelix Acetate is an injectable gonadotropin-releasing hormone antagonist (GnRH antagonist). Abarelix Acetate is primarily used in oncology to reduce the amount made in patients with advanced symptomatic prostate cancer for which no other treatment options are available.
