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Prodotti farmaceutici attivi

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  • COA
nome del prodotto Triamcinolon Acetonide
N. CAS: 76-25-5
Molecular Formular C24H31FO6
EINECS n 200-948-7
Purezza 99%
Aspetto esteriore polvere

Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, relieve the discomfort of mouth soresand in nasal spray form as an over-the-counter relief for allergic and perennial allergic rhinitis.It is a more potent derivative of triamcinolone, being about 8 times as potent as prednisone.

Triamcinolone acetonide is an acetate derivative of triamcinolone A. It's a moderate glucocorticoid. The effect is similar to that of Triancillon, with anti-inflammatory, anti-pruritus and vasoconstriction effects, water and sodium retention effect is weak, among which the anti-inflammatory effect is stronger and lasting. The anti-inflammatory activity of 4mg triamcinolone was approximately equivalent to 5mg of prednisolone or 20mg of hydrocortisone. Triamcinolone acetonide is a long-acting adrenocorticosteroid, which has anti-inflammatory, anti-pruritus and vasoconstriction effects similar to that of Triancillone. Its anti-inflammatory and anti-allergic effect is strong and lasting, the effect is 20 a 30 times greater than cortisone. Triamcinolone acetonide has anti-inflammatory, anti-pruritus and vasoconstriction effects. Its anti - inflammatory and anti - allergic effects are strong and lasting. To dermatitis and other skin diseases, can be wiped by the skin, closed application wrapped therapy, and absorbed by the skin. Triamcinolone acetonide is extremely well tolerated for topical use.

ITEMS OF ANALYSIS SPECIFICATIONS RESULT
Aspetto esteriore Polvere cristallina bianca o quasi bianca almost white crystalline powder
Solubilità Practically insoluble in water,sparingly soluble in ethanol Conforme
Identificazione(E,TLC) Complies with the standard Conforme
Rotazione ottica specifica +110°~+117° +115°
Acqua No more than 2.0% 0.28%
Solventi residui Methanol≤3000ppm 188ppm
Dimethyformamide≤880ppm n.d
Acetone ≤ 5000 ppm 413ppm
Dichloromethane≤600ppm n.d
Particle size 90%≤30um Conforme
Related substances
Impurity B No more than 0.2% 0.05%
Inpurity C No more than 0.15% 0.02%
Unspecified impurity No more than 0.1% 0.06%
Total impurities No more than 0.5% 0.26%
Saggio 97%~103% 98.3%
Conclusione Comply with the requirements of EP 9.0.

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