productnaam:telapriston
synoniemen:Cdb 4124;proellex;telapriston (acetaat);jvbgzfrptrksbb-mjbqoybxsa-n
CAS:198414-31-2 / 198414-30-1
MF:C31H39NO5
MW:505.64506
telapriston (CAFE), as telapristone acetate (proposed brand names Proellex, Progenta; former code name CDB-4124), is een synthetisch, steroidal selective progesterone receptor modulator (SPRM) related to mifepristone which is under development by Repros Therapeutics for the treatment of breast cancer, endometriose, and uterine fibroids.It was originally developed by the National Institutes of Health (NIH), and, as of 2017, is in phase II clinical trials for the aforementioned indications.In addition to its activity as an SPRM, the drug also has some antiglucocorticoid activity.
