Ime: Teduglutide
št. CAS. : 197922-42-2
Zaporedje: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp- Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp
Molekulska formula: C164H252N44O55S
Molekularna teža : 3752.28
Čistost: >98.0%
Videz: beli prah
Vir: sintetični
Videz: Bel liofiliziran prašek
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology.
Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4.
Teduglutide is a glucagon-like peptide-2 (GLP-2); regeneration, maintenance, and repair of the intestine.
