Nomen: Teduglutide
CAS No. : 197922-42-2
Sequentia: eius Gly Asp-Gly Ser Phe-Ser Aspis Glu-Met Asn Thr Ile-Leu Asp-Asn-Leu Ala-Ala Arg Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp
Formulae hypotheticae: C164H252N44O55S
M. pondus : 3752.28
Puritas: >98.0%
Aspectus: cerussa
Source: synthetica
Aspectus: White Lyophilized pulveris
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology.
Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4.
Teduglutide is a glucagon-like peptide-2 (GLP-2); regeneration, maintenance, and repair of the intestine.
