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Active Pharmaceuticals

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  • Specifications
  • depictio producti
  • Product Syntaxis
  • COA
Product Name Quininum Sulphate
Cas 804-63-7
MF C40H50N4O8S
M. pondus 746.91
liquescens punctum 173~177ºC
EINECS 212-359-2
Odor Proprium
Gradus Medchine Gradus
Specification 99%
Aspectus Album pulveris crystallini

Quinine sulphate s a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in addition to being consumed straight.

Quinine is a kind of alkaloid derived from the bark of the cinchona tree.It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.Quinine was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

ITEMS Test Standard TEST RESULT
DESCRIPTION A white or almost white powder Complies
SOLUILITAS' Very soluble in water; solutum in ethanol (96%) Complies
MELTING POINT 233-235 C 234C
SPECIFIC OPTICAL ROTATION -223-229° (C=2, 0.1M HCl) -241º
SULPHATED ASH ≤0.1% 0.05%
BARIUM This product is 0.2g, dissolved in 10ml water, add dilute sulfuric acid 1ml, 15 minutes, turbidity shall not occur Complies
THE RELATED IMPURITIES ≤ 1.5% 0.9%
LOSS ON DRYING 6.0%-10.0% 8.0%
RESIDUE ON IGNITION ≤ 0.15% 0.05%
PH pH=2.0-3.0 2.5
ASSAY 99.0%-101.0% 99.2%
TEST CONCLUSION The product complies with BP2009 and CP2005 standards

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