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Plaaslike verdowingsmiddels

» Farmaseutiese middels » Plaaslike verdowingsmiddels

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CAS No.: 22801-44-1
Engelse Naam: Mepivacaine
English Nickname: MFCD00243006 /N-(2,6-Dimethylphenyl)-1-Piperidinecarboxamide
Digtheid: 1.077g/cm3
Kookpunt: 383.1oC at 760 mmHg
Smeltpunt(oC): NVT
Molecular Formular: C15H22N2O
Molecular weight: 246.34800
Flitspunt: 185.5oC

Mepivicaine is 'n plaaslike verdowingsmiddel van die amiedtipe. Mepivicaine as 'n redelik vinnige aanvang en medium duur en staan ​​bekend onder die eie name as Carbocaine en Polocaine. Mepivicaine word gebruik in plaaslike infiltrasie en streeksnarkose. Sistemiese absorpsie van plaaslike verdowingsmiddels lewer effekte op die kardiovaskulêre en sentrale senuweestelsels. By bloedkonsentrasies bereik met normale terapeutiese dosisse, veranderinge in hartgeleiding, opgewondenheid, vuurvastheid, kontraktiliteit, en perifere vaskulêre weerstand is minimaal.

Mepivacaine is an amide type local anesthetic.Mepivacaine has a fairly quick effect (faster than procaine) and moderate duration (short of procaine) and is sold in various names including carp and procaine.

Mepivacaine went public in the United States in the 1960s.The product is suitable for penetration, nerve block and epidural anesthesia. Methylpivacaine is only effective at large doses, so this approach should not be used.

Mepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Car and Polo.

Mepivacaine became available in the United States in the 1960s.Mepivacaine is used in any infiltration and regional anesthesia.It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties

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