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Local Anesthetic Drugs

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  • Product Description
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CAS No.: 22801-44-1
English Name: Mepivacaine
English Nickname: MFCD00243006 /N-(2,6-Dimethylphenyl)-1-Piperidinecarboxamide
Density: 1.077g/cm3
Boiling Point: 383.1oC at 760 mmHg
Melting Point(oC): N/A
Molecular Formular: C15H22N2O
Molecular  weight: 246.34800
Flash Point: 185.5oC

Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.

Mepivacaine is an amide type local anesthetic.Mepivacaine has a fairly quick effect (faster than procaine) and moderate duration (short of procaine) and is sold in various names including carp and procaine.

Mepivacaine went public in the United States in the 1960s.The product is suitable for penetration, nerve block and epidural anesthesia. Methylpivacaine is only effective at large doses, so this approach should not be used.

Mepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Car and Polo.

Mepivacaine became available in the United States in the 1960s.Mepivacaine is used in any infiltration and regional anesthesia.It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties

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