Lanreotide Acetate CAS:127984-74-1

Lanreotide is a synthetic analogue of somatostatin, a naturally occurring inhibitory hormone which blocks the release of several other hormones, including growth hormone, thyroid-stimulating hormone (TSH), insulin and glucagon. Lanreotide binds to the same receptors as somatostatin, although with higher affinity to peripheral receptors, and has similar activity. Avšak, while somatostatin is quickly broken down in the body (within minutes), lanreotide has a much longer half-life, and produces far more prolonged effects.

Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas. In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma, a rare tumor of the pituitary gland which secretes TSH.

Lanreotide also shows activity against non-endocrine tumors, a, along with other somatostatin analogues, is being studied as a possible general antitumor agent.

Vzhľad: Biely prášok
Čistota(HPLC): ≥98,0 %
Jediná nečistota(HPLC): ≤ 1,0 %
Obsah acetátu(HPLC): 5.0%~12.0%
Obsah vody (Karl Fischer): ≤ 10,0 %