英語名: Lanreotide Acetate
CAS:127984-74-1
アッセイ:98%+
分子量:0グラム/モル
分子式: C54H69N11O10S2
外観: 白い粉
備考: 研究専用, 人間用ではない
Lanreotide is a synthetic analogue of somatostatin, a naturally occurring inhibitory hormone which blocks the release of several other hormones, including growth hormone, thyroid-stimulating hormone (TSH), insulin and glucagon. Lanreotide binds to the same receptors as somatostatin, although with higher affinity to peripheral receptors, and has similar activity. However, while somatostatin is quickly broken down in the body (within minutes), lanreotide has a much longer half-life, and produces far more prolonged effects.
Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas. In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma, a rare tumor of the pituitary gland which secretes TSH.
Lanreotide also shows activity against non-endocrine tumors, そして, along with other somatostatin analogues, is being studied as a possible general antitumor agent.
外観: 白い粉
純度(HPLC): ≧98.0%
単一の不純物(HPLC): ≤1.0%
アセテート含有量(HPLC): 5.0%~12.0%
含水量 (カール・フィッシャー): ≤10.0%
