L-Epinephrine CAS:51-43-4

L-adrenaline, also known as L-Epinephrine, is extracted from the adrenal medulla of domestic animals (cattle and sheep) or synthesized by artificial methods, and has agonistic effects on both α and β receptors. Adrenaline is a hormone secreted by chromophores in the adrenal medulla. It is mainly involved in the regulation of sympathetic nervous system.

L-Epinephrine is white or off-white crystalline powder, odorless and bitter in taste. Very slightly soluble in water, insoluble in organic solvents such as ethanol and chloroform, soluble in mineral acid or sodium hydroxide solution. Unstable in neutral or alkaline aqueous solution, saturated aqueous Chemicalbook solution shows weak alkaline reaction. Its hydrochloride is commonly used, easily soluble in water, 0.1% aqueous solution pH 2.5~5.0, the product and its salt are easily decomposed and oxidized to pink to brownish red when encountering oxides, bases, light and heat.

L-adrenaline is used for allergic diseases: subcutaneous or intramuscular injection can treat allergic diseases, such as anaphylaxis, urticaria, bronchial asthma, hoof lobe inflammation, etc. It is also effective for allergic reactions caused by immune serum and vaccines.

L-adrenaline is applied in combination with local anesthetics: 0.5~1ml of 0.1% adrenaline solution is added to every 100ml of local anesthetics to constrict local blood vessels and delay the absorption of local anesthetics, which can prolong the anesthesia time and reduce the toxic reaction of anesthetics. 4. Topical use as local hemostatic drug: 1:5000~1:100,000 solution is used locally to make local blood vessels constrict and stop bleeding of nasal mucosa, uterus, gums or surgical site, etc.