Nome del prodotto:Acetato di Gestonorone / Gestonorone Acetate
CAS:31981-44-9
Sinonimi:17-Idrossi-19-norpregn-4-ene-3,20-dione 17-acetato;17acetato di alfa-idrossi-19-norprogesterone-17alfa;19-Nor-17alfa-idrossiprogesterone acetato,Norhydroxyprogesterone Acetate
Formula molecolare:C22H30o4
Peso molecolare:358.47
EINECS n.:250-882-8
Densità:1.16g/cm3
Punto di fusione:228-230℃
Gestonorone acetate, or gestronol acetate, also known as norhydroxyprogesterone acetate, is a progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups which was developed in the early 1960s but was never marketed.
Gestonorone acetate has been found to consistently inhibit ovulation at an oral dosage of 10 mg/day in combination with 50 μg/day oral ethinylestradiol.Weak or no endometrial effects were observed at an oral dosage of 100 mg/day, basal vacuoles appeared at 130 a 140 mg/day, and full endometrial secretory transformation occurred at 220 mg/day.
ARTICOLI DI PROVA |
SPECIFICA |
RISULTATI |
Descrizione |
Polvere cristallina bianca o quasi bianca |
polvere bianca |
Identificazione |
A.B. |
Positivo |
Saggio |
97.0~103,0% |
99.1% |
Perdita all'essiccamento |
1.0%max |
0.25% |
Punto di fusione |
222~228°C |
227°C |
Impurità organiche volatili |
soddisfa il requisito. |
Conforme |
Sostanze correlate |
soddisfa il requisito. |
Conforme |
Solventi residui |
soddisfa il requisito. |
Conforme |
Dimensione delle particelle |
100%20 micron |
Conforme |
Conclusione |
The specification conform with USP30 standard |